Tejesvi Mysore
Chief Executive Officer
Anna Maria Pirttilä
Scientific Advisor
About Us
We have developed highly effective, antimicrobial coated catheters to prevent HAIs. We have a dedicated team of experts involved in the design and development of coated catheters aiming to minimize the risks of HAIs. The company was established as a spin-out from the University of Oulu, where R&D activities were carried out by the founders of the company.
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Juhani Lahdenperä
Business Development Manager
Tomi Järvinen
Chairman of the Board
Healthcare Associated Infections (HAIs) affect 4 million people annually, resulting in 16 million extra days of hospital stay, amounting to € 7 billion direct costs. HAIs cause more deaths annually than those caused by prostate and breast cancer.
Catheter-associated Urinary Tract Infections (CAUTIs) affected more than 93,300 patients in the USA in 2011 (CDC).
Prevalence of HAI
– European countries: 7.1% (ECDC 2002)
– Finland 9.1%
– USA: 4.5% (9.3 infections per 1000 patient-days and 1.7 million affected patients)
Prevalence of CAUTI
– Most frequent type of HAI
– Related to urinary catheter use
– 36% in the USA
– 27% in Europe
– Estimated 93,300 UTIs in acute care hospitals in 2011 in the United States (CDC data)
Solution
CHAIN Antimicrobials Ltd’s lead product, peptide-coated catheters (PAC) show high promise as an effective and safe means to prevent CAUTI, since the molecule has
These properties support the claim that PACs could be optimal for preventing CAUTI.
Technology
CHAIN Antimicrobials Ltd. has developed highly effective antimicrobial peptides. The CHAIN peptides are coated on catheters to prevent bacterial and fungal infections. We have conducted several in-vitro tests on our products with positive results.
The PACs are intended to prevent bacterial attachment on the urinary catheters
In-vitro experiments have shown that the peptides can kill or inhibit bacteria associated with UTI
Preclinical trials are under way to test efficacy in animal models.